RESZON® Strongyloidiasis IgG4 Rapid Test
This webpage content is intended for Healthcare Professionals only, not for general public. Registered under Act 737
MDA Registration Number: IVDC7526826-233770
- Rapid immunochromatography assay for qualitative detection of specific IgG4 antibodies to Strongyloides stercoralis
- Specimen: Human whole blood, serum, plasma
- Fast result within 15-25 minutes
- Simple to perform & no special equipment required
For professional in vitro diagnostic use only.
SPECIFICATION
| Platform | Immunochromatographic Assay |
| Format | Cassette |
| Detection | Specific IgG4 antibodies to Strongyloides stercoralis |
| Specimen | Human whole blood, serum & plasma |
| Specimen volume | 35 μl |
| Sensitivity | 96.6% |
| Specificity | 91.2% |
| Storage | 2-30°C |
| Shelf Life* | 24 months |
*From date of manufacture
WHAT IS STRONGYLOIDIASIS?
Strongyloidiasis is a chronic human parasitic infection mainly caused by Strongyloides stercoralis, a soil-transmitted helminth (STH) capable of persisting in the human host for decades through a unique autoinfection cycle. This ability allows larvae to reinvade the host without external re-exposure, making strongyloidiasis fundamentally different from other STH infections and a major reason it often remains undetected for years.
Globally, strongyloidiasis was estimated to affect 613.9 million people in 2017, with the highest burden reported in tropical and subtropical regions. The South-East Asia, African, and Western Pacific regions together accounted for approximately 76.1% of global infections.
Many infected individuals develop chronic, asymptomatic infections that may persist for decades – or even a lifetime – because of the parasite’s ability to autoinfect. Of particular concern is the risk of progression to hyperinfection syndrome or disseminated strongyloidiasis following immunosuppression, especially with corticosteroid therapy. Therefore, screening for Strongyloides infection is recommended before initiating immunosuppressive therapy in individuals at risk of infection.
WHY CHOOSE RESZON® STRONGYLOIDIASIS IgG4
RAPID TEST KIT?
High Diagnostic Performance for Accurate Detection
- Sensitivity: 96.6% supports early detection
- Specificity: 91.2% reliable screening results
Proven Performance Across Diverse Settings
- Evaluated across multiple countries (Switzerland, Thailand, Iran, Malaysia) and populations2,3,4,5
- Demonstrates good and consistent performance
- Suitable for diagnosis, screening, and public health programs
Suitable for Clinically Challenging Cases, such as Patients with:
- Unexplained eosinophilia
- Chronic gastrointestinal symptoms
- Recurrent or unexplained skin manifestations
- Asthma or respiratory symptoms with eosinophilia
- Unexplained Gram-negative sepsis
Fast Results
- Within 15 minutes (serum/plasma samples)
- Within 25 minutes (whole blood samples)
WHO ARE AT HIGHER RISK OF SEVERE DISEASE
(HYPERINFECTION/DISSEMINATED STRONGYLOIDIASIS)?
IMMUNOSUPPRESSED INDIVIDUALS
- Patients infected with human immunodeficiency virus (HIV) or human T-lymphotropic virus type 1 (HTLV-1)
- Patients receiving chemotherapy for cancer
- Solid organ transplant recipients
- Hematopoietic stem cell (bone marrow) transplant recipients
- Advanced chronic kidney disease (CKD)
- Patients with autoimmune or inflammatory diseases receiving immunosuppressive drugs (e.g. rheumatoid arthritis)
- Patients with severe malnutrition or other causes of impaired cellular immunity
PATIENTS RECEIVING CORTICOSTEROID THERAPY
Both short-term and long-term systemic corticosteroid therapy
can increase the risk of Strongyloides hyperinfection syndrome
PATIENTS WITH HAEMATOLOGICAL MALIGNANCIES
- Leukemia
- Lymphoma and other haematological malignancies
|
Cat. No. |
Product Description |
Test Specimen* |
Product Format |
Intended Use |
Intended Use |
Storage Temp. |
Packing Size |
|---|---|---|---|---|---|---|---|
|
RSS-RD0101-25 |
RESZON® Strongyloidiasis IgG4 Rapid Test Rapid Test |
S/P/WB |
Cassette |
Detection of specific IgG4 antibodies to Strongyloides stercoralis |
For Professional Use |
2-30oC |
25 T/ Kit |
|
RSS-RD0101A-25 |
RESZON® Strongyloidiasis IgG4 Rapid Test Rapid Test (with disposable dropper) |
S/P/WB |
Cassette |
Detection of specific IgG4 antibodies to Strongyloides stercoralis |
For Professional Use |
2-30oC |
25 T/ Kit |
|
RSS-RD0101B-25 |
RESZON® Strongyloidiasis IgG4 Rapid Test (with disposable dropper, alcohol swab and lancet) |
S/P/WB |
Cassette |
Detection of specific IgG4 antibodies to Strongyloides stercoralis |
For Professional Use |
2-30oC |
25 T/ Kit |
* S – Serum; P – Plasma; WB – Whole Blood; T – Test
References:
- Ashiri, A., Rafiei, A., Noordin, R., Anuar, S.A., Teimoori, A., Ansari-Moghaddam, B., Beiromvand, M. (2025) Strongyloides stercoralis prevalence and diagnostic efficacy of an IgG4 rapid test in an eosinophilic population in Khuzestan Province, southwestern Iran. Parasit Vectors 18, 291.
- Nickel B, Krebs C, Ruf MT, Anuar NS, Noordin R. (2024) An evaluation of a lateral flow rapid diagnostic test for Strongyloides stercoralis infection. Acta Trop. 2024; 258:107336.
- Wongphutorn P, Noordin R, Anuar NS, Worasith C, Kopolrat KY, Homwong C, Tippayawat P, Techasen A, Pitaksakurat O, Sithithaworn J, Eamudomkarn C, Sithithaworn P. (2024) Examination of Diagnostic Performance of New IgG4 Rapid Test Compared with IgG- and IgG4-ELISAs to Investigate Epidemiology of Strongyloidiasis in Northeast Thailand. Am J Trop Med Hyg 2024; 110(2):254-262.
- Noordin R, Osman, Kalantari N, Anuar NS, Gorgani-Firouzjaee T, Sithithaworn P, Juri NM, Rahumatullah A. (2022) A point-of-care cassette test for detection of Strongyloides stercoralis. Acta Tropica 2022; 226:106251.
- Tamarozzi F, Guevara ÁG, Anselmi M, Vicuña Y, Prandi R, Marquez M, Vivero S, Robinzón Huerlo F, Racines M, Mazzi C, Denwood M, Buonfrate D. (2023) Accuracy, acceptability, and feasibility of diagnostic tests for the screening of Strongyloides stercoralis in the field (ESTRELLA): a cross-sectional study in Ecuador. Lancet Glob Health. 2023 May;11(5):e740-e748.